WAV files are not so good with metadata. And they can be so large that they cause drop outs if you are streaming them wireless. My 192kHz WAV files cause a lot of buffering on my network. But the fLAC versions play fie in real time. And you can forget about trying to steam 384kHz WAV files. Its a constant buffering playback. Those ones I have to play back via a wired connection.
The uncompressed FLAC files are also smaller then their WAV equivalent. But isn't so much about size really. It's not so easy to get music in WAV format unless you buy a CD.