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Thread: Johns Hopkins Medical Centre - World Coronavirus infection Map by Country.

  1. #3981
    Join Date: Aug 2009

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    Quote Originally Posted by dave2010 View Post
    Sorry to disagree, but I don't think the maths works for herd immunity - or at least not yet. In the long term it might, but on the one hand we perhaps don't want too many people to get it, and if we could get the numbers low enough it might go away, but on the other hand for herd immunity we need more people to get it - more even than the current rate of infection would suggest.!
    It's a long-term strategy, balancing the infection rate against hospital admissions. I've seen estimates that say up to 40% of the population have already had the virus although many have shown little or no symptoms. As antibody testing increases that estimate will become more accurate. As time goes on the percentage will increase to herd immunity levels.

    The trick is to achieve herd immunity without overwhelming the health care system. So it will take time. There's currently no evidence that you can catch it more than once.
    Current Lash Up:

    TEAC VRDS 701T > Sony TAE1000ESD > Krell KSA50S > JM Labs Focal Electra 926.

  2. #3982
    Join Date: Aug 2009

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    Quote Originally Posted by Sherwood View Post
    No. Herd immunity is frequently misunderstood. It is typically referenced when determining the proportion of a susceptible population that needs to be immunised in order to provide effective control of an infectious disease such as measles, TB, and polio. The reasoning is that even if the whole population is not immunised, the pool of susceptible uninfected individuals is sufficiently low to prevent widespread infection. The estimates for herd immunity to be effective vary but at the very minimum, it is around 70% of the population. If herd immunity is to be achieved in the UK this would require over 40m individuals to be infected, with the huge burden of mortality and morbidity that would entail. Furthermore, if COVID 19 is like influenza, and mutates slightly each year, herd immunity will be rapidly lost and the whole population (or a large percentage of the population) will require re-immunisation each year.

    The reason that case mortality rates have fallen faster than the rate of new infections is that better treatments have been developed. However, any gains from reduced case mortality rates may well be offset by rapidly rising infection rates which is what we are currently experiencing. Anybody who understands exponential growth will appreciate the consequences of the reproduction rate rising appreciably above unity.
    I think we all understand what herd immunity is, it isn't a difficult concept to grasp. I think we all understand what exponential growth is too. It's possible to reach herd immunity without exponential growth, it is just a question of time.

    People more susceptible to the virus need to remain isolating and take extra precautions. Ultimately they will benefit the most from herd immunity. You don't want the R value to fall too low (unless it is a result of reaching herd immunity) otherwise you will never reach herd immunity. Likewise you don't want it going too high as it may overwhelm health services. So it is being managed with local lockdowns, social distancing, mask wearing etc. Those things alone will never eradicate the virus. That seems to be the bit that some people don't get.
    Current Lash Up:

    TEAC VRDS 701T > Sony TAE1000ESD > Krell KSA50S > JM Labs Focal Electra 926.

  3. #3983
    Join Date: Jan 2008

    Location: Wrexham, North Wales, UK

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    Quote Originally Posted by Macca View Post
    It's a long-term strategy, balancing the infection rate against hospital admissions. I've seen estimates that say up to 40% of the population have already had the virus although many have shown little or no symptoms. As antibody testing increases that estimate will become more accurate. As time goes on the percentage will increase to herd immunity levels.

    The trick is to achieve herd immunity without overwhelming the health care system. So it will take time.
    Indeed.

    Quote Originally Posted by Macca
    I think we all understand what herd immunity is, it isn't a difficult concept to grasp. I think we all understand what exponential growth is too. It's possible to reach herd immunity without exponential growth, it is just a question of time.
    Absolutely. Ultimately, allowing nature to take its course [in tandem with controlling the spread of the virus as much as possible, taking all reasonable and necessary precautions], is the ONLY real way of getting through this.

    Marco.
    Main System

    Turntable: Heavily-modified Technics SL-1210MK5G [Mike New bearing/ETP platter/Paul Hynes SR7 PSU & reg mods]. Funk Firm APM Achromat/Nagaoka GL-601 Crystal Record Weight/Isonoe feet & boots/Ortofon RS-212D/Denon DL-103GL in Denon PCL-300 headshell with Funk Firm Houdini/Kondo SL-115 pure-silver cartridge leads.

    Paul Hynes MC head amp/SR5 PSU. Also modded Lentek head amp/Denon AU-310 SUT.

    Other Cartridges: Nippon Columbia (NOS 1987) Denon DL-103. USA-made Shure SC35C with NOS stylus. Goldring G820 with NOS stylus. Shure M55E with NOS stylus.

    CD Player: Audiocom-modified Sony X-777ES/DAS-R1 DAC.

    Tape Deck: Tandberg TCD 310, fully restored and recalibrated as new, by RDE, plus upgraded with heads from the TCD-420a. Also with matching TM4 Norway microphones.

    Preamps: Heavily-modified Croft Charisma-X. LDR Stereo Coffee. Power Amps: Tube Distinctions Copper Amp fitted with Tungsol KT-150s. Quad 306.

    Cables & Sundries: Mark Grant HDX1 interconnects and digital coaxial cable, plus Mark Grant 6mm UP-LCOFC Van Damme speaker cable. MCRU 'Ultimate' mains leads. Lehmann clone headphone amp with vintage Koss PRO-4AAA headphones.

    Tube Distinctions digital noise filter. VPI HW16.5 record cleaning machine.

    Speakers: Tannoy 15MGs in Lockwood cabinets with modified crossovers. 1967 Celestion Ditton 15.


    Protect your HUMAN RIGHTS and REFUSE ANY *MANDATORY* VACCINE FOR COVID-19!

    Also **SAY NO** to unjust 'vaccine passports' or certificates, which are totally incompatible with a FREE society!!!


  4. #3984
    Join Date: Jan 2008

    Location: Wrexham, North Wales, UK

    Posts: 110,012
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    Quote Originally Posted by Sherwood View Post
    Furthermore, if COVID 19 is like influenza, and mutates slightly each year, herd immunity will be rapidly lost and the whole population (or a large percentage of the population) will require re-immunisation each year.
    Same would apply with any vaccine, which even if safe, would never be 100% effective over a long period of time. Therefore, as I've said (also Macca), ultimately herd immunity , however long it takes, is the only real solution, and with that, Covid-19 will *eventually* go the way of Swine Flu or SARS... Until the next strain of corornavirus comes along!

    Yes, with the way we're living now, I believe that these types of outbreaks will become more commonplace in the years to come.

    Marco.
    Main System

    Turntable: Heavily-modified Technics SL-1210MK5G [Mike New bearing/ETP platter/Paul Hynes SR7 PSU & reg mods]. Funk Firm APM Achromat/Nagaoka GL-601 Crystal Record Weight/Isonoe feet & boots/Ortofon RS-212D/Denon DL-103GL in Denon PCL-300 headshell with Funk Firm Houdini/Kondo SL-115 pure-silver cartridge leads.

    Paul Hynes MC head amp/SR5 PSU. Also modded Lentek head amp/Denon AU-310 SUT.

    Other Cartridges: Nippon Columbia (NOS 1987) Denon DL-103. USA-made Shure SC35C with NOS stylus. Goldring G820 with NOS stylus. Shure M55E with NOS stylus.

    CD Player: Audiocom-modified Sony X-777ES/DAS-R1 DAC.

    Tape Deck: Tandberg TCD 310, fully restored and recalibrated as new, by RDE, plus upgraded with heads from the TCD-420a. Also with matching TM4 Norway microphones.

    Preamps: Heavily-modified Croft Charisma-X. LDR Stereo Coffee. Power Amps: Tube Distinctions Copper Amp fitted with Tungsol KT-150s. Quad 306.

    Cables & Sundries: Mark Grant HDX1 interconnects and digital coaxial cable, plus Mark Grant 6mm UP-LCOFC Van Damme speaker cable. MCRU 'Ultimate' mains leads. Lehmann clone headphone amp with vintage Koss PRO-4AAA headphones.

    Tube Distinctions digital noise filter. VPI HW16.5 record cleaning machine.

    Speakers: Tannoy 15MGs in Lockwood cabinets with modified crossovers. 1967 Celestion Ditton 15.


    Protect your HUMAN RIGHTS and REFUSE ANY *MANDATORY* VACCINE FOR COVID-19!

    Also **SAY NO** to unjust 'vaccine passports' or certificates, which are totally incompatible with a FREE society!!!


  5. #3985
    Join Date: May 2016

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    I'm Geoff.

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    To repeat the point, herd immunity requires either an effective one time immunisation (as we have for TB, polio etc), or a long term immunity to reinfection once infected. Neither of these conditions are met or certain as yet.

    Of course we need the reproduction rate to be low (i.e. below unity) because herd immunity is not an effective strategy for this disease. No competent public health specialist or epidemiologist would suggest otherwise.

  6. #3986
    Join Date: Aug 2009

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    I'm Martin.

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    Influenza is a covid virus and it seems to be forgotten that a lot of people die from that every year and have done for centuries. The swine flu of 2009 is estimated to have killed half a million people globally. Remember us having a lockdown and a big panic over that? No, neither do I. But it was declared as a pandemic by the WHO https://www.ctvnews.ca/who-declares-...ate%20severity.
    Current Lash Up:

    TEAC VRDS 701T > Sony TAE1000ESD > Krell KSA50S > JM Labs Focal Electra 926.

  7. #3987
    Join Date: Jan 2008

    Location: Wrexham, North Wales, UK

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    Quote Originally Posted by Sherwood View Post
    To repeat the point, herd immunity requires either an effective one time immunisation (as we have for TB, polio etc), or a long term immunity to reinfection once infected. Neither of these conditions are met or certain as yet.
    And to also reapeat: it will take TIME, but I believe it will happen.

    Of course we need the reproduction rate to be low (i.e. below unity) because herd immunity is not an effective strategy for this disease. No competent public health specialist or epidemiologist would suggest otherwise.
    It will be, if the right criteria is met, some of which you've outlined.

    Marco.
    Main System

    Turntable: Heavily-modified Technics SL-1210MK5G [Mike New bearing/ETP platter/Paul Hynes SR7 PSU & reg mods]. Funk Firm APM Achromat/Nagaoka GL-601 Crystal Record Weight/Isonoe feet & boots/Ortofon RS-212D/Denon DL-103GL in Denon PCL-300 headshell with Funk Firm Houdini/Kondo SL-115 pure-silver cartridge leads.

    Paul Hynes MC head amp/SR5 PSU. Also modded Lentek head amp/Denon AU-310 SUT.

    Other Cartridges: Nippon Columbia (NOS 1987) Denon DL-103. USA-made Shure SC35C with NOS stylus. Goldring G820 with NOS stylus. Shure M55E with NOS stylus.

    CD Player: Audiocom-modified Sony X-777ES/DAS-R1 DAC.

    Tape Deck: Tandberg TCD 310, fully restored and recalibrated as new, by RDE, plus upgraded with heads from the TCD-420a. Also with matching TM4 Norway microphones.

    Preamps: Heavily-modified Croft Charisma-X. LDR Stereo Coffee. Power Amps: Tube Distinctions Copper Amp fitted with Tungsol KT-150s. Quad 306.

    Cables & Sundries: Mark Grant HDX1 interconnects and digital coaxial cable, plus Mark Grant 6mm UP-LCOFC Van Damme speaker cable. MCRU 'Ultimate' mains leads. Lehmann clone headphone amp with vintage Koss PRO-4AAA headphones.

    Tube Distinctions digital noise filter. VPI HW16.5 record cleaning machine.

    Speakers: Tannoy 15MGs in Lockwood cabinets with modified crossovers. 1967 Celestion Ditton 15.


    Protect your HUMAN RIGHTS and REFUSE ANY *MANDATORY* VACCINE FOR COVID-19!

    Also **SAY NO** to unjust 'vaccine passports' or certificates, which are totally incompatible with a FREE society!!!


  8. #3988
    Join Date: Jan 2008

    Location: Wrexham, North Wales, UK

    Posts: 110,012
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    Quote Originally Posted by Macca View Post
    Influenza is a covid virus and it seems to be forgotten that a lot of people die from that every year and have done for centuries. The swine flu of 2009 is estimated to have killed half a million people globally. Remember us having a lockdown and a big panic over that? No, neither do I. But it was declared as a pandemic by the WHO https://www.ctvnews.ca/who-declares-...ate%20severity.
    A very salient point! And you have to ask yourself WHY...?? WHY all the panic this time, over something that is arguably less serious, and not before? What's the driving force behind the creation of panic this time?

    Any thoughts on that?

    Your point on influenza is also very relevant.

    Marco.
    Main System

    Turntable: Heavily-modified Technics SL-1210MK5G [Mike New bearing/ETP platter/Paul Hynes SR7 PSU & reg mods]. Funk Firm APM Achromat/Nagaoka GL-601 Crystal Record Weight/Isonoe feet & boots/Ortofon RS-212D/Denon DL-103GL in Denon PCL-300 headshell with Funk Firm Houdini/Kondo SL-115 pure-silver cartridge leads.

    Paul Hynes MC head amp/SR5 PSU. Also modded Lentek head amp/Denon AU-310 SUT.

    Other Cartridges: Nippon Columbia (NOS 1987) Denon DL-103. USA-made Shure SC35C with NOS stylus. Goldring G820 with NOS stylus. Shure M55E with NOS stylus.

    CD Player: Audiocom-modified Sony X-777ES/DAS-R1 DAC.

    Tape Deck: Tandberg TCD 310, fully restored and recalibrated as new, by RDE, plus upgraded with heads from the TCD-420a. Also with matching TM4 Norway microphones.

    Preamps: Heavily-modified Croft Charisma-X. LDR Stereo Coffee. Power Amps: Tube Distinctions Copper Amp fitted with Tungsol KT-150s. Quad 306.

    Cables & Sundries: Mark Grant HDX1 interconnects and digital coaxial cable, plus Mark Grant 6mm UP-LCOFC Van Damme speaker cable. MCRU 'Ultimate' mains leads. Lehmann clone headphone amp with vintage Koss PRO-4AAA headphones.

    Tube Distinctions digital noise filter. VPI HW16.5 record cleaning machine.

    Speakers: Tannoy 15MGs in Lockwood cabinets with modified crossovers. 1967 Celestion Ditton 15.


    Protect your HUMAN RIGHTS and REFUSE ANY *MANDATORY* VACCINE FOR COVID-19!

    Also **SAY NO** to unjust 'vaccine passports' or certificates, which are totally incompatible with a FREE society!!!


  9. #3989
    Join Date: Aug 2009

    Location: Staffordshire, England

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    I'm Martin.

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    Quote Originally Posted by Sherwood View Post
    To repeat the point, herd immunity requires either an effective one time immunisation (as we have for TB, polio etc), or a long term immunity to reinfection once infected. Neither of these conditions are met or certain as yet.

    Of course we need the reproduction rate to be low (i.e. below unity) because herd immunity is not an effective strategy for this disease. No competent public health specialist or epidemiologist would suggest otherwise.
    Not in public, no. But if they had another solution I'd imagine that they might mention that. So far, nothing. What are your grounds for stating that herd immunity is not an effective strategy?
    Current Lash Up:

    TEAC VRDS 701T > Sony TAE1000ESD > Krell KSA50S > JM Labs Focal Electra 926.

  10. #3990
    Join Date: Aug 2009

    Location: Staffordshire, England

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    Quote Originally Posted by Marco View Post
    A very salient point! And you have to ask yourself WHY...?? WHY all the panic this time, over something that is arguably less serious, and not before?

    Any thoughts on that?

    Your point on influenza is also very relevant.

    Marco.
    When it started nothing was known about the virus. So they erred on the side of caution. Also it did become clear quite quickly that C-19 was more contagious than 'flu virus and was more virulent in its effects on the average individual than swine flu. So there was a danger of the health system being overwhelmed which there was not with the swine flu. It is clearly more serious than swine flu.

    My point was that there was a pandemic in 2009 and a lot of people died and it wasn't big news, barely news at all in fact. But as C-19 is big news joe punter gets to hear about it and then even one death from it is 'One death too many!'
    Current Lash Up:

    TEAC VRDS 701T > Sony TAE1000ESD > Krell KSA50S > JM Labs Focal Electra 926.

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