You will notice a difference bi-wiring. Take care as I did and thought it was better due to "Ive changed something it must be better thing us Hifi fanatics can suffer". I was using Linn K400 cable which is a dedicated biamp/wire cable and about as good as have found for the money. I recently single wired my speakers using just the bottom section of the K400 placing the jumpers on (carefully of course!) and to my amazement and annoyance the sound was far more OF A WHOLE, image had more solidity and bass was tighter more rhythmical. Basically in my case biwireing actually confused the sound. I then bought some Sterling black Mamba speaker cable and can see me ever changing it to be honest as its fantastic and one of the few cables to be significantly better than the Linn K400 stuff.
If you are using mono block amps or say Linn/Arcam type bi amping using another power amp then it sounds better but thats bi amping.
Paul
Onkyo 875, Monitor Audio RX6 GW,Monitor audio RX centre GW,Monitor Audio BFX rears, REL QUAKE,Arcam CD73t CD ,Russ Andrews Yello mains cabling & PBJ interconnects,Sterling Black Mamba speaker cable.